CD44 Archives - Baylor College of Medicine Blog Network

AKAP8 and the delicate balance between normal and metastatic states

March 12, 2020 AKAP8, alternative splicing, Breast Cancer, CD44, CLSTN1, metastatis, Research

A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. “Our laboratory investigates cellular

From The Labs

CD44 variants prompt different cancer cell behaviors

February 21, 2019 alternative splicing, Breast Cancer, cancer heterogeneity, cancer plasticity, CD44, Metastasis, Research, resistance to treatment

Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack

From The Labs

G-quadruplex helps breast cancer survive

February 15, 2018 alternative splicing, Breast Cancer, CD44, G-quadruplex

For breast cancer, expressing the protein CD44s, instead of CD44v, has a survival advantage. And one of the goals of Dr. Chonghui Cheng lab is to

From The Labs

Image of the Month: Mechanisms of cancer survival

August 1, 2017 alternative splicing, cancer survival, CD44, EGFR signaling, Image of the month, PI3K/Akt signaling

Among other studies, the lab of Dr. Chonghiu Cheng is pioneering research projects to better undertsand the role alternative splicing plays in cancer. “We have been

From The Labs

CD44s, not CD44v, contributes to cancer survival

July 25, 2017 Akt pathway, alternative splicing, cancer survival, CD44, EGFR signaling

Cells may stray away from their normal function in a number of ways. For example, it’s been known for some time that in a number