Intestinal stem cells have a hard time ‘forgetting’ an encounter with inflammation
Inflammation in the gut leaves long-term marks on intestinal stem cells that affect their response to future challenges.
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bone marrow transplant
Can changing the gut microbiome alter the course of a disease?
A simple, safe dietary intervention has an effect on the gut microbiome and metabolites in these patients.
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Microbiome’s link to severe graft-versus-host disease suggests potential treatment
This is one of the first studies to provide an explanation and a potential solution for the imbalance in the gut microbiome that exacerbates GVHD.
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Promising approach to mitigate complications of leukemia treatment
The findings support further assessing this approach to treat aggressive blood cancers and ultimately improve outcomes in patients.
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Waking up sleeping beauty – persistent IFN-gamma awakens and activates stem cells via BST2
The researchers show that persistent IFNγ mediates the exhaustion of blood stem cells via BST2 expression.
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“Off-the-shelf” cells are safe and effective to treat viral infections
A bone marrow transplant can be a life-saving treatment for patients with certain cancers and other serious illnesses that have not responded to conventional chemotherapies.
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