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Search Results for: Meng Wang

meng-wang-photo

Researching molecular treatments to promote healthy aging

December 9, 2016 Dr. Meng Wang, Huffington Center on Aging, molecular and human genetics, TAMEST

As we get older, the risk of developing diseases such as Alzheimer’s and cancer significantly increase. Dr. Meng Wang is researching the use of natural

Low-glucose sensor in the brain promotes blood glucose balance

July 11, 2023 anoctamin 4, blood glucose, glucose-excited neurons, glucose-inhibited neurons, ion channel, Research, type 1 diabetes

The findings suggest that glucose-sensing neurons in the brain are important for whole body glucose regulation, including during diabetes.

obesity-scale-photo

Serotonin 2C receptor linked to obesity and maladaptive behavior

January 11, 2023 behavior, genetics of obesity, POMC neurons, Research, serotonin 2C receptor

A study by Baylor College of Medicine, the University of Cambridge and the University of Exeter makes the case for a novel role for serotonin 2C receptor.

Overactive brain circuit causes anorexia in animal model

May 12, 2022 anorexia, brain circuit, dopamine, DRD1, Research, serotonin

Restoring the normal activity of a particular overactive brain circuit improved anorexia in an animal model of the condition.

Targeting MAPK4 may offer a new therapeutic opportunity for TNBC

January 27, 2022 AKT, cancer therapy, MAPK4, PI3K, PI3K inhibitor, Research, triple-negative breast cancer

MAPK4 seems to be involved in promoting triple-negative breast cancer growth and its resistance to certain therapies.

Expanding the diagnosis for Xia-Gibbs Syndrome

September 7, 2021 diagnosis, missense mutations, rare disease, Research, Xia-Gibbs syndrome

Researchers at Baylor College of Medicine have validated a new type of genetic mutation that causes Xia-Gibbs Syndrome, a rare genetic disorder.

Eating for hunger or pleasure? This is how the brain handles these feeding behaviors

August 26, 2021 brain circuit, GABA A receptor, hunger, ion channel, Research, serotonin, serotonin 1B receptor, serotonin 2C receptor

The researchers found that each type of feeding is wired by its own independent circuit that does not influence the other type.

Targeting MAPK4 emerges as a promising therapy for prostate cancer

February 23, 2021 Akt pathway, androgen receptor, cancer therapy, castration-resistant prostate cancer, MAPK4, Prostate Cancer, Research

Inhibiting MAPK4 simultaneously inactivated both androgen receptor and AKT and stopped cancer growth in animal models.

Novel PROTAC has a two-front improvement

September 3, 2020 BTK, PROTAC, protein degrader, Research, reversible covalent chemical binder

Researchers developed a novel PROTAC with enhanced intracellular accumulation and improved ability to neutralize target proteins inside cells.

CAR T cell therapy makes strides in tackling Hodgkin lymphoma

August 11, 2020 blood cancer, CAR T cell therapy, fludarabine, Hodgkin lymphoma, Research

CAR-T cell therapy has been used to treat Hodgkin lymphoma with remarkable success for the first time in an early phase clinical trial.

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