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A novel intervention to potentially improve the outcome of children with malnutrition
Colic: Symptoms and relief
Astrocytes directly regulate brain circuits involved in memory consolidation
Fro-yo or ice cream? Is one healthier than the other?

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Search Results for: Estes

Confocal microscopy image of a human intestinal enteroid.

Image of the Month: Human intestinal enteroids

January 2, 2024 human intestinal enteroids, organoids, Research, rotavirus

Human intestinal enteroids have revolutionized the study of gastrointestinal viruses like rotavirus.

Human mini guts reveal new insights into Cronkhite-Canada syndrome and potential new therapies

November 16, 2023 Cronkhite-Canada syndrome, human intestinal organoids, polyps, Rare Diseases, Research, serotonin

The work also highlights the value of human organoid technology to improve the understanding of any disease and identify potential clinical applications.

Llama power: can tiny llama nanobodies improve norovirus anti-viral therapies?

November 14, 2023 llama antibodies, M4 nanobody, nanobodies, Norovirus, norovirus GII.4, Research, viral neutralization

Llama nanobodies may offer an option for treating norovirus, a global health problem for which there are no vaccines or antiviral drugs.

Researchers are making strides in the fight against gastroenteritis

March 7, 2023 cellular injury, CLIC pathway, gastroenteritis, GII4, human norovirus entry mechanism, Norovirus, Research

The findings provide insight into the viral infection process, highlighting unique pathways and targets for developing effective therapeutics.

Artificial intelligence reveals a never-before described 3D structure in rotavirus spike protein

June 9, 2022 ALphaFold2, gastroenteritis, N-acetyllactosamine, Research, rotavirus, spike protein, VP8*, X-Ray crystallography

The findings are an example of how viruses can evolve by incorporating structurally distinct modules with similar functionality.

Miniature model of the human nose reveals early events of SARS-CoV-2 and RSV infection

February 22, 2022 COVID-19, human nose model, human nose organoid, palivizumab, Research, RSV, SARS-CoV-2

Researchers anticipate that the human nose organoid system would help accelerate the transfer of lab-developed therapeutics to the bedside.

It takes a village (of cells) to heal the intestine

November 9, 2021 healing the intestine, intestinal epithelium, Research, rotavirus infection, stem cells, tuft cells

A rotavirus infection stimulates the coordinated activities of a variety of cell types that repair the damage to the intestinal epithelium.

Dr. Helen Heslop elected to the National Academy of Medicine

October 26, 2021 adoptive immunotherapy, cancer immunotherapy, National Academy of Medicine;, Research, translational research

Election to the National Academy of Medicine recognizes outstanding professional achievement and commitment to service.

Naturally occurring antibodies recognize many different noroviruses

July 22, 2021 monoclonal antibodies, neutralizing antibodies, Norovirus, Research

The findings are big step toward developing targeted treatments and vaccines against noroviruses attacking the gastrointestinal tract.

A new mechanism of cisplatin resistance in cancer, and how to reverse it

April 22, 2021 ACTL6A, cancer resistance to therapy, cisplatin, DNA repair, epigenetic chromatin remodeling, panobinostat, Research

ACLT6A overexpression confers cancer cells resistance to cisplatin, and researchers found a way to reverse it.

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