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Monday, June 16, 2025
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From The Labs

Baylor College of Medicine Human Genome Sequencing Center celebrates 20 years since the completion of the Human Genome Project

April 13, 2023 20 year anniversary,  BCM-HGSC,  Human Genome Project,  Research

BCM-HGSC contributed 10% of the human genome and continues generating data and new technologies to integrate genome analysis into diagnoses and therapies.

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From The Labs

Preventing liver damage in animal models of Alagille syndrome

April 11, 2023 Alagille syndrome,  antisense oligonucleotide,  biliary tree,  cholestasis,  JAG1,  POGLUT1,  Research

The findings show that it is possible to promote the formation of a near-normal biliary tree in animals that already have a poorly developed biliary tree.

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From The Labs

Researchers discover a vulnerability of acute myeloid leukemia

April 6, 2023 Acute myeloid leukemia,  AML,  epigenetics,  gene regulation,  PU.1,  Research,  SWI/SNF

Exploiting this vulnerability resulted in rapid tumor regression in animal models of AML.

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From The Labs

Uncovering the first steps driving antibiotic resistance

April 4, 2023 antibiotic resistance,  ciprofloxacin,  DNA-damage response,  general stress response,  Research,  RNA polymerase

The findings offer new opportunities to interfere with the development of antibiotic resistance and help turn the tide on this global health threat.

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From The Labs

And the 2022 ATC Core of the Year Award goes to…

March 30, 2023 BCM Core labs,  Core of the year,  Research,  RNA in situ hybridization core

The results of the survey to unveil the 2022 Core of the Year are out!

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From The Labs

Uncovering drivers of glioma-related epilepsy

March 28, 2023 astrocytes,  brain cancer,  epilepsy,  Glioma,  potassium,  Research,  seizures

A combination of animal model and patient studies reveals new possibilities to control glioma-related seizures and tumor growth.

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From The Labs

Researchers pave the way for solutions to problems affecting preterm infants

March 23, 2023 cortisol,  FGF19,  growth failure,  necrotizing enterocolitis,  newborns,  preterm babies,  Research,  stress hormone

The findings could be an important step toward improved neonate care, particularly preterm neonates.

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From The Labs

TRISH to study how the human body and mind respond to spaceflight

March 21, 2023 Axiom Mission 2,  ISS,  life in space,  Research,  Space Medicine,  Spaceflight

The findings also can give insights into medical conditions and treatments to improve human health on Earth.

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From The Labs

Astrocytes mediate deficits in learning and memory triggered by social isolation

March 16, 2023 animal behavior,  astrocyte function,  calcium channel,  GABA,  Research,  social isolation,  TRPA1

The researchers propose a mechanism by which changes in the environment influence astrocyte function which in turn affects animal behavior.

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From The Labs

Clinical trial finds that oral drug MK-0616 substantially reduces ‘bad’ cholesterol

March 14, 2023 atherosclerosis,  bad cholesterol,  Cardiovascular Disease,  LDL-cholesterol,  MK-0616,  PCSK9 inhibitor,  Research

MK-016 could offer another potential option to achieve guideline-recommended LDL-C levels resulting in reduction of cardiovascular risk.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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