From The Labs Archives - Page 9 of 93 - Baylor College of Medicine Blog Network

How neurotransmitters work together to detect odors

November 28, 2023 co-transmission, dopamine, GABA, neuromodulation, neurotransmitters, odor detection, sSAC

Neurons producing neurotransmitters GABA and dopamine can differentially modulate different target neurons involved in the sense of smell.

From The Labs

Human mini guts reveal new insights into Cronkhite-Canada syndrome and potential new therapies

November 16, 2023 Cronkhite-Canada syndrome, human intestinal organoids, polyps, Rare Diseases, Research, serotonin

The work also highlights the value of human organoid technology to improve the understanding of any disease and identify potential clinical applications.

From The Labs

Llama power: can tiny llama nanobodies improve norovirus anti-viral therapies?

November 14, 2023 llama antibodies, M4 nanobody, nanobodies, Norovirus, norovirus GII.4, Research, viral neutralization

Llama nanobodies may offer an option for treating norovirus, a global health problem for which there are no vaccines or antiviral drugs.

From The Labs

Team develops imaging method to capture previously inaccessible coordination of tiny hair-like cilia in live organisms

November 9, 2023 cilia, cilia movement, female reproductive system, imaging technique, Infertility, optical coherence tomography (OCT), Research

This new method gives researchers access to study previously inaccessible roles of cilia in the female reproductive system and infertility.

Web of red with green splotches show neural connections in the visual pathway of the brain

From The Labs

Image of the Month: Neural connections in the visual pathway of the brain

November 7, 2023 cytoskeletal proteins, Image of the month, Microscopy, NeuN, neuronal connections, Research, viual pathway

Like an elaborate superhighway, an intricate network of neuronal projections keeps neurons in the visual pathway connected.

From The Labs

Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits

November 2, 2023 Autism, Brain, gut microbiome, intestinal endothelium, L. reuteri, oxytocin, Research, secretin

The details of how gut resident bacteria L. reuteri can affect the gut and other organs are beginning to fall into place.

From The Labs

eIF4A emerges as a potential Achilles’ heel for triple-negative breast cancer

October 31, 2023 cancer vulnerability, eIF4A, Research, triple-negative breast cancer, Zotatifin

Targeting eIF4A to interfere with the synthesis of proteins the cancer needs to grow is producing promising results.

From The Labs

5D4 disrupts several molecular pathways, including MYC, that lead to cancer growth

October 26, 2023 5D4, Breast Cancer, cancer inhibitor, MYC, ovarian cancer, PARP inhibitor, Research, TopBP1

The findings strongly support the potential use of TopBP1 inhibitors as a targeted cancer therapy.

A graphic illustration of a family that appear as silhouettes filled with germs.

From The Labs

Can changing the gut microbiome alter the course of a disease?

October 24, 2023 bone marrow transplant, butyrate, clinical trial, dietary intervention, graft-versus-host disease, gut microbiome, potato starch, Research

A simple, safe dietary intervention has an effect on the gut microbiome and metabolites in these patients.

From The Labs

Deep brain stimulation induces more healthy neurons and sustained memory benefits in Rett animal models

October 19, 2023 brain-derived neurotrophic factor, deep brain stimulation, MECP2, Research, Rett Syndrome

DBS results in a significant and long-lasting improvement to memory in Rett animal models strongly suggesting evaluating this approach to treat Rett patients.