solid tumors Archives - Baylor College of Medicine Blog Network

Long-term survival supports the potential benefit of CAR T cell therapy to treat solid tumors

February 27, 2025 CAR T cell therapy, Clinical Trials, disease free, longest survival, neuroblastoma, Research, solid tumors

An 18-year survivor of neuroblastoma is believed to represent the longest reported remission to date in a patient treated with chimeric antigen receptor (CAR) T cell therapy.

From The Labs

Sprinter and marathoner CAR T cells reveal their distinct cancer-killing behavior

February 4, 2025 cancer treatment, CAR T cell, Research, solid tumors

The study lays a foundation for designing CAR molecules that maximize antitumor activity beyond B cell malignancies.

Pre- and post-infusion three-dimensional imaging shows that infused GPC3 CAR T cells induce significant antitumor responses in patients.

From The Labs

From bench to bedside and back: CAR T cells armed with IL-15 show promise in treating solid cancers

January 28, 2025 cancer treatment, CAR T cells, Clinical Trials, IL-15, Research, solid tumors

Researchers relate their journey to finding a promising method to address CAR T cell challenges in treating solid tumors.

From The Labs

CAR NKT cells, a promising step forward in the treatment of solid tumors

November 10, 2020 CAR NK T cells, clinical trial, Immunotherapy, neuroblastoma, Research, solid tumors

An ongoing clinical trial shows that human CAR NKT cells are safe and, in 1 of 3 patients, induced regression of metastatic lesions.

From The Labs

Special delivery of IL-7 signaling makes all the difference for CAR T cells fighting solid tumors

May 15, 2018 brain tumor, CAR T cells, IL7, Immunotherapy, Research, solid tumors

Since he was in college, Thomas Shum wanted to pursue a career in cancer research. As he advanced in his studies, he was able to