Rotavirus protein NSP4 manipulates gastrointestinal disease severity
The findings suggest that regulating NSP4 could lead to new strategies to prevent or treat rotavirus infections.
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Gastrointestinal discomfort? Here is a new explanation for how rotavirus makes you sick
This study is the first to show that rotavirus-altered lipid metabolism in the intestine plays a role in the disease.
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Image of the Month: Human intestinal enteroids
Human intestinal enteroids have revolutionized the study of gastrointestinal viruses like rotavirus.
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Baylor College of Medicine recognizes research excellence with DeBakey Awards
Baylor College of Medicine honors faculty for their outstanding published scientific contributions to clinical and basic science research.
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Artificial intelligence reveals a never-before described 3D structure in rotavirus spike protein
The findings are an example of how viruses can evolve by incorporating structurally distinct modules with similar functionality.
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Image (video) of the Month: human intestinal organoid after infection with rotavirus
This video placed first in the 2021 FASEB BioArt contest: video category. Congratulations, JT Gebert and the Hyser lab!
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How a few rotavirus can cause severe gastrointestinal disease
Using intercellular calcium waves, rotavirus amplifies its ability to cause disease beyond the cells it directly infects.
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Slow-growing rotavirus mutant reveals early steps of viral assembly
Rotavirus is responsible for more than 130,000 deaths annually in infants and children younger than five years. The virus causes severe, dehydrating diarrhea as it
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Mystery solved, rotavirus VP3 is a unique capping machine
After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led
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‘Give me the calcium!’ Tulane virus takes over cellular calcium signaling to replicate
Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome
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