rotavirus Archives - Baylor College of Medicine Blog Network

Gastrointestinal discomfort? Here is a new explanation for how rotavirus makes you sick

January 11, 2024 DGAT1, diarrhea, gastrointestinal tract, GI viruses, human intestinal enteroids, poor nutrient absorption, Research, rotavirus

This study is the first to show that rotavirus-altered lipid metabolism in the intestine plays a role in the disease.

Confocal microscopy image of a human intestinal enteroid.

From The Labs

Image of the Month: Human intestinal enteroids

January 2, 2024 human intestinal enteroids, organoids, Research, rotavirus

Human intestinal enteroids have revolutionized the study of gastrointestinal viruses like rotavirus.

From The Labs

Baylor College of Medicine recognizes research excellence with DeBakey Awards

August 18, 2022 biophotonic technology, COVID-19, DeBakey M.D. Award for Excellence in Research., hematopoiesis, Research, rotavirus, thoracic aortic disease, tissue regeneration

Baylor College of Medicine honors faculty for their outstanding published scientific contributions to clinical and basic science research.

From The Labs

Artificial intelligence reveals a never-before described 3D structure in rotavirus spike protein

June 9, 2022 ALphaFold2, gastroenteritis, N-acetyllactosamine, Research, rotavirus, spike protein, VP8*, X-Ray crystallography

The findings are an example of how viruses can evolve by incorporating structurally distinct modules with similar functionality.

From The Labs

Image (video) of the Month: human intestinal organoid after infection with rotavirus

March 1, 2022 calcium channels, calcium signalling pathways, FASEB BioArt contest, Research, rotavirus, viroporins

This video placed first in the 2021 FASEB BioArt contest: video category. Congratulations, JT Gebert and the Hyser lab!

From The Labs

How a few rotavirus can cause severe gastrointestinal disease

December 8, 2020 ADP, calcium waves, diarrhea, Research, rotavirus, serotoning, vomiting

Using intercellular calcium waves, rotavirus amplifies its ability to cause disease beyond the cells it directly infects.

From The Labs

Slow-growing rotavirus mutant reveals early steps of viral assembly

June 23, 2020 lipid droplets, NSP2, phosphomimetics, Research, rotavirus, viroplasm

Rotavirus is responsible for more than 130,000 deaths annually in infants and children younger than five years. The virus causes severe, dehydrating diarrhea as it

From The Labs

Mystery solved, rotavirus VP3 is a unique capping machine

April 23, 2020 mRNA capping, Research, rotavirus, VP3

After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led

From The Labs

‘Give me the calcium!’ Tulane virus takes over cellular calcium signaling to replicate

November 12, 2019 gastrointestinal virus, human norovirus, NS1-2, Research, rotavirus, Tulane virus, viroporin

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome

Still image to accompany July 2019's Video of the Month (Hyser lab) Cells expressing a fluorescent calcium sensor (green) were infected with rotavirus, a virus that causes acute gastroenteritis. The rotavirus-infected cells (pink) trigger an intercellular calcium wave that increases calcium in surrounding uninfected cells. (Scale bar = 100 μm; courtesy of the Hyser lab).

From The Labs

Video of the Month: A calcium storm

July 2, 2019 calcium indicator, gastroenteritis, Research, rotavirus, video

From the Labs opens July 2019 with a Video of the Month, showing the calcium ‘storm’ rotavirus triggers in infected cells. Calcium signaling in rotavirus

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