Research Archives - Page 15 of 79 - Baylor College of Medicine Blog Network

Variants of MRTFB gene linked to novel neurodevelopmental disorder

May 9, 2023 actin-binding protein, fruit fly, MRTFB gene, neurodevelopmental disorder, Research, undiagnosed disease

The findings open new avenues to investigate mechanisms that lead to this disorder, offering ideas toward a future treatment for the disease.

From The Labs

Neurons lead the way in the development of astrocytes

May 4, 2023 astrocyte development, GABA B receptor, neurons, Research

Neurons trigger a complex pattern of events, some of them unexpected, that direct astrocyte development in a region-specific manner.

From The Labs

Image of the Month: The Liver’s biliary tree

May 2, 2023 Alagille syndrome, bile, biliary tree, Image of the month, Research

A healthy mouse liver typically shows a well-developed biliary tree through which bile flows into the intestine to help absorb fats and eliminate toxins.

From The Labs

Understanding path to multiple sclerosis leads to a potentially improved therapy

Apr 27, 2023 autoimmune response, bezafibrate, fingolimod, inflammation, Multiple Sclerosis, myelin degradation, Research, S1P, VLCFA

The findings have clinical implications not just in the treatment of MS but also for other neurodegenerative conditions.

From The Labs

A map to study exRNA, a novel form of cell-to-cell communication

Apr 25, 2023 exRNA, exRNA-eCLIP intersection analysis, liquid biopsy, Research, RNA binding proteins

The exRNA map is a valuable resource to accurately implement early detection and monitor disease processes.

From The Labs

How a mutation in the SKD3 enzyme can cause MGCA7 disease

Apr 20, 2023 crystal structure, enzyme activity, MGCA7 disease, Research, SKD3

The researchers propose the first mechanism by which non-catalytic domain mutations in SKD3 can lead to MGCA7.

From The Labs

Protein Beclin-1 is key for uterine remodeling and the establishment of pregnancy

Apr 18, 2023 apoptosis, autophagy, Beclin-1, Pregnancy, Research, stem cells, uterine development

The findings have encouraged exploring the development of practical applications in the fields of both contraceptives and infertility.

From The Labs

Baylor College of Medicine Human Genome Sequencing Center celebrates 20 years since the completion of the Human Genome Project

Apr 13, 2023 20 year anniversary, BCM-HGSC, Human Genome Project, Research

BCM-HGSC contributed 10% of the human genome and continues generating data and new technologies to integrate genome analysis into diagnoses and therapies.

From The Labs

Preventing liver damage in animal models of Alagille syndrome

Apr 11, 2023 Alagille syndrome, antisense oligonucleotide, biliary tree, cholestasis, JAG1, POGLUT1, Research

The findings show that it is possible to promote the formation of a near-normal biliary tree in animals that already have a poorly developed biliary tree.

From The Labs

Researchers discover a vulnerability of acute myeloid leukemia

Apr 6, 2023 Acute myeloid leukemia, AML, epigenetics, gene regulation, PU.1, Research, SWI/SNF

Exploiting this vulnerability resulted in rapid tumor regression in animal models of AML.