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From The Labs

Gene splicing gone wrong leads to aggressive medulloblastoma

August 27, 2024 alternative splicing,  medulloblastoma,  OTX2,  pediatric brain cancer,  PPHLN1,  Research

Disturbing OTX2’s gene-splicing ability reduced tumor growth, opening possibilities for improved treatments.

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From The Labs

A potential new therapeutic target for Group 3 medulloblastoma

August 8, 2024 CAR T cell,  grade3-medulloblastoma,  Immunotherapy,  pediatric brain cancer,  protogenin,  Research

Researchers identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma in the developing brain.

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From The Labs

CAR T cell therapy for pediatric brain cancer warrants further study

June 18, 2024 C7R,  CAR T cells,  clinical trial,  Glioma,  pediatric brain cancer,  Research

This study shows that this therapy can effectively get to the tumor, and the addition of C7R safely augments antitumor activity.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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