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From The Labs

New mouse model mimics progression of Parkinson’s disease

October 3, 2024 disease model,  G51D mutation,  Parkinson's Disease,  Research,  SNCA gene

This model can help identify new disease biomarkers and test therapies that could alter its progression, maybe even prevent the condition.

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Allison hugging her husband while he's in a hospital bed.
Momentum

“The Stars Aligned”: One warrior’s journey with Parkinson’s

April 11, 2024 American Ninja Warrior,  Dan L Duncan Comprehensive Cancer Center,  deep brain stimulation surgery,  Parkinson's Disease

Allison Toepperwein and her husband Steven share their experience with deep brain stimulation for the treatment of movement disorders.

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From The Labs

Fungal infection in the brain produces changes like those seen in Alzheimer’s disease

October 17, 2023 Alzheimer's Disease,  amyloid precursor protein,  Brain,  C. albicans,  cnadidalysin,  fungus,  Parkinson's Disease,  Research,  Saps

This work potentially contributes an important new piece of the puzzle regarding the development of Alzheimer’s disease.

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From The Labs

Brain sphingolipid metabolism is closely involved in Gaucher disease

July 19, 2022 Gaucher disease,  glia,  glucosylceramide,  lipid metabolism,  lysosomes,  neurodegenerative disease,  neurons,  Parkinson's Disease,  Research,  sphingolipid

Disruption of sphingolipid metabolism led to neurodegeneration in animal models, revealing a new molecular path to Gaucher’s disease.

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jankovic-photo
Momentum

Throwback Thursday: Fighting Parkinson’s disease

November 29, 2018 Dr. Joseph Jankovic,  Nicole Blanton,  Parkinson's Disease,  Throwback Thursday

For decades, researchers and physicians at Baylor College of Medicine and beyond have been working to find the cause and cure for movement disorders such

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From The Labs

There are new key players in Parkinson’s disease

August 30, 2018 alpha-synuclein,  ceramide,  fruit fly,  Neurodegeneration,  Parkinson's Disease,  phospholipase PLA2G6,  Research,  retromer

The roadmap that may lead to Parkinson’s disease has a number of ‘landmarks,’ gene variants and cellular defects known to be associated with the disease.

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featured-toepperwein
Momentum

The ultimate race: Powering through Parkinson’s disease

April 11, 2018 Allison Toepperwein,  Dr. Joseph Jankovic,  Neurology,  Parkinson's Disease

“Coach Neuendorff, you might as well get that ambulance ready, because I’m coming in first! I don’t care what it takes!” I was 14 with

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From The Labs

Childhood condition poses risk for Parkinson’s disease later in life

January 22, 2018 Gaucher disease,  GBA gene,  Lysosome Storage Disorders,  Parkinson's Disease

In recent years, defects in the glucocerebrosidase (GBA) gene have been identified as significant risk factors for Parkinson’s disease and deficiencies in this gene also

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From The Labs

Juvenile Batten disease, a problem with cellular waste management

March 29, 2017 AKT,  Alzheimer's,  cellular waste,  Huntington’s,  Juvenile Batten disease,  lysosomes,  Neuroscience,  Parkinson's Disease,  TFEB

Like a large dynamic city, a cell carries out many activities that generate waste. Waste needs to be disposed of properly in order for the

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From The Labs

A pill to prevent Alzheimer’s disease might someday be a reality

January 18, 2017 Alzheimer's Disease,  fruit fly model,  Genetics,  mouse model,  Nuak1,  Parkinson's Disease,  tau

Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer’s disease, according to scientists at

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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