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From The Labs

AI accelerates the discovery of genes associated with neurodevelopmental disorders

March 11, 2025 AI modeling,  Autism Spectrum Disorder,  developmental delay,  epilepsy,  Genes,  neurodevelopmental disorders,  Research

The researchers hope that their models will also lead to patient diagnoses, and future studies will assess this possibility.

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From The Labs

Researchers reveal genetic basis of severe forms of EBF3-associated neurodevelopmental disorders

April 26, 2022 Autism,  EBF3,  HADDS,  neurodevelopmental disorders,  Research,  zinc finger domain

Patients with some gene variants affecting a zinc finger region of EBF3 suffer from a more severe form of the condition.

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Brain-with-DNA-featured
From The Labs

The discovery of genes like PAX5 improves diagnostic testing for neurodevelopmental disorders, and more

April 14, 2022 genetic diagnosis,  neurodevelopmental disorders,  PAX5,  Research,  undiagnosed diseases

Discovering new genes that are linked to undiagnosed diseases has relevant scientific and clinical consequences as well as important personal implications for patients.

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From The Labs

Single cells reveal genetic connections of neurodevelopmental disorders

September 29, 2020 autism spectrum disorders,  computational framework,  epilepsy,  Genetics,  neurodevelopmental disorders,  Research

A novel computational approach helps researchers identify connections between genes involved in different neurodevelopmental disorders.

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From The Labs

This two-step approach can expedite finding answers to complex genetic conditions

November 16, 2017 animal model,  Autism,  cell line,  HIPK2,  MeCP2 duplication syndrome,  neurodevelopmental disorders,  Neurological disorders,  PP2A

To function normally, the human brain requires the right amount of a number of proteins, including MeCP2. Having twice the normal amount of MeCP2, the

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From The Labs

Variations in gene ATAD3A can result in distinct neurological syndromes

October 21, 2016 ATAD3A,  fruit fly,  Human genetics,  mitochondria,  miyophagy,  neurodevelopmental disorders

Research has revealed that a group of rare neurological syndromes for which there was no cause can be the result of variations in the gene

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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