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From The Labs

The road to uncovering a novel mechanism for disposing of misfolded proteins

October 20, 2020 alpha1-antitrypsin (AAT) deficiency,  conformational diseases,  liver deficiency,  lung disease,  Man1b1,  misfolded proteins,  Neurodegeneration,  Research

The discovery of the cause of a rare liver disease in babies may lead to preventing more common neurological disorders occurring in late age.

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From The Labs

To be or not to be in the ER, that is the question

August 25, 2020 BMP4,  endoplasmic reticulum,  ERAD,  misfolded proteins,  NGLY1,  proteasomal degradation,  Research

Researchers discovered a new way cells can dispose of misfolded proteins that may help better understand human NGLY1 deficiency.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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