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From The Labs

Sorting out what drives Huntington’s disease

July 12, 2018 fruit fly,  high-throughput,  huntingtin,  Huntington’s disease,  neurological disease,  Research

Neurological diseases are typically associated with a multitude of molecular changes. But out of thousands of changes in gene expression, which ones are actually driving

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From The Labs

Of fruit flies, genes and aortic aneurysms

June 21, 2018 aortic aneurysm,  ari-1,  fruit fly,  parkin,  Research

One of the goals of Dr. Hugo Bellen’s lab is to conduct genetic screens in the fruit fly to identify genes that cause neurodevelopmental and

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From The Labs

Fruit flies: ‘living test tubes’ to rapidly screen potential disease-causing human genes

May 22, 2018 fruit fly,  Model organisms,  Research,  TBX2,  undiagnosed diseases

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and

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From The Labs

The humble fruit fly continues to boost biomedical discovery

April 5, 2018 animal models,  CRIMIC,  CRISPR-Mediated Integrated Cassette,  Drosophila,  fruit fly,  genetic diseases,  Research

For more than 100 years, the humble fruit fly has been used to understand fundamental biological processes and has been a crucial tool for rapid

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From The Labs

Image of the Month: Neuron-muscle synapses in the fruit fly

January 4, 2017 ATAD3A,  Drosophila,  fruit fly,  Genetics,  heart conditions,  low muscular tone,  neurological syndromes,  Neuroscience

Certain human gene variants of ATAD3A can cause rare neurological syndromes characterized by global developmental delay, low muscular tone and visual, neurological and heart problems. The

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From The Labs

Variations in gene ATAD3A can result in distinct neurological syndromes

October 21, 2016 ATAD3A,  fruit fly,  Human genetics,  mitochondria,  miyophagy,  neurodevelopmental disorders

Research has revealed that a group of rare neurological syndromes for which there was no cause can be the result of variations in the gene

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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