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Pre- and post-infusion three-dimensional imaging shows that infused GPC3 CAR T cells induce significant antitumor responses in patients.
From The Labs

From bench to bedside and back: CAR T cells armed with IL-15 show promise in treating solid cancers

January 28, 2025 cancer treatment,  CAR T cells,  Clinical Trials,  IL-15,  Research,  solid tumors

Researchers relate their journey to finding a promising method to address CAR T cell challenges in treating solid tumors.

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From The Labs

CAR T cell therapy for pediatric brain cancer warrants further study

June 18, 2024 C7R,  CAR T cells,  clinical trial,  Glioma,  pediatric brain cancer,  Research

This study shows that this therapy can effectively get to the tumor, and the addition of C7R safely augments antitumor activity.

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Microscopy image of purple leukemia cells amongst healthy pink cells
From The Labs

Promising approach to mitigate complications of leukemia treatment

October 6, 2022 alloimmune defense receptor,  bone marrow transplant,  CAR T cells,  GvH disease,  leukemia,  leukemia treatment complications,  Research

The findings support further assessing this approach to treat aggressive blood cancers and ultimately improve outcomes in patients.

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From The Labs

Fighting cancer with rejection-resistant, ‘off-the-shelf’ therapeutic T cells

August 20, 2020 alloimmune defense receptor,  cancer therapy,  CAR T cells,  Off-the-shelf therapeutic T cells,  Research

Baylor College of Medicine researchers extend the life and effectiveness of off-the-shelf, cancer-fighting immune T cells.

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From The Labs

Special delivery of IL-7 signaling makes all the difference for CAR T cells fighting solid tumors

May 15, 2018 brain tumor,  CAR T cells,  IL7,  Immunotherapy,  Research,  solid tumors

Since he was in college, Thomas Shum wanted to pursue a career in cancer research. As he advanced in his studies, he was able to

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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