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From The Labs

Image of the Month: What causes myotonic dystrophy, type1

September 5, 2017 alternative splicing,  CELF1 and MBNL proteins,  CTG repeat,  CUGexp,  DM1,  DMPK gene,  MEF2 transcription factor,  muscular dystrophy,  myotonic dystrophy,  RNA splicing

Myotonic dystrophy, type 1 (DM1) is the second most common cause of muscular dystrophy and numerous other muscle disorders that affect tens of thousands of

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From The Labs

Image of the Month: Mechanisms of cancer survival

August 1, 2017 alternative splicing,  cancer survival,  CD44,  EGFR signaling,  Image of the month,  PI3K/Akt signaling

  Among other studies, the  lab of Dr. Chonghiu Cheng is pioneering research projects to better undertsand the role alternative splicing plays in cancer. “We have been

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From The Labs

CD44s, not CD44v, contributes to cancer survival

July 25, 2017 Akt pathway,  alternative splicing,  cancer survival,  CD44,  EGFR signaling

Cells may stray away from their normal function in a number of ways. For example, it’s been known for some time that in a number

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From The Labs

How do muscles grow up? Check alternative splicing

January 30, 2017 alternative splicing,  Genetics,  heart muscle,  muscular disorders,  muscular dystrophy,  myotonic dystrophy,  skeletal muscle

Growing up is a complex affair, even for muscles. In the mouse, for instance, newborn muscles grow into adult muscles within the first three weeks

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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