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From The Labs

DAPK3 emerges as a new regulator of migration of triple-negative breast cancer cells

October 8, 2024 cancer cell migration,  DAPK3,  desmoplakin,  LUZP1,  Research,  triple-negative breast cancer

The researchers’ next steps include studying how DAPK3 promotes TNBC migration and assess its potential value as a therapeutic target.

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From The Labs

New mouse model mimics progression of Parkinson’s disease

October 3, 2024 disease model,  G51D mutation,  Parkinson's Disease,  Research,  SNCA gene

This model can help identify new disease biomarkers and test therapies that could alter its progression, maybe even prevent the condition.

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From The Labs

Center for NextGen Therapeutics helps match researchers to molecules

October 1, 2024 BCM Centers,  drug discovery,  multispecific drugs,  NextGen Therapeutics,  Research

Dr. Jin Wang explains what the new Center for NextGen Therapeutics has to offer to researchers at Baylor College of Medicine, across the Texas Medical Center and beyond.

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From The Labs

Anticipating treatment response in triple negative breast cancer

September 26, 2024 B cells,  Research,  response to cancer treatment,  triple-negative breast cancer

A new blood biomarker discovered in triple negative breast cancer patients could potentially indicate response to treatment.

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From The Labs

Intestinal stem cells have a hard time ‘forgetting’ an encounter with inflammation

September 24, 2024 bone marrow transplant,  GVHD,  inflammation,  intestinal stem cells,  Research

Inflammation in the gut leaves long-term marks on intestinal stem cells that affect their response to future challenges.

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From The Labs

Medical student-mentor teams in research: Adel Hassan and Dr. Nandan Mondal share their experience with SOAR

September 19, 2024 cardiovascular research,  medical students in research,  mentor-student teams,  Research,  SOAR

A medical student and his mentor share how the SOAR program brought them together to conduct basic science research and how the experience is shaping their careers.

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From The Labs

P-bodies are part of the survival strategies of acute myeloid leukemia

September 12, 2024 Acute myeloid leukemia,  AML,  cancer survival,  P bodies,  Research,  tumor suppressor genes

The findings suggest that P-bodies might be an Achilles’ heel of acute myeloid leukemia, opening new avenues for developing anticancer agents to treat this condition.

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A healthy spinach salad with chicken and cranberries.
From The Labs

Trying to balance hunger and guilty pleasures? Penk neurons are here to help

September 10, 2024 brain circuits in feeding,  DBB-Penk neurons,  hunger,  Obesity,  pleasure eating,  Research

Penk neurons in the brain support an ideal, balanced feeding pattern in unexpected ways.

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From The Labs

Researchers discovered novel and unique neural signature for depression

September 5, 2024 anhedonia,  beta activity in the ACC,  Depression,  neural signature,  Research

This signal could improve diagnosis and monitoring of symptoms of severe depression and other anhedonia-related psychiatric conditions.

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From The Labs

Image of the Month: Aging signs

September 3, 2024 Aging,  cell nucleus,  Hutchinson-Gilford Progeria Syndrome,  lamin A,  Research

Overexpression of lamin A (red) causes structural changes to the cell nucleus that are associated with aging.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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