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From The Labs

Image of the Month: The greenhouse inside the lab

July 5, 2023 agriculture,  better foods,  crops,  food securiry,  greenhouse,  Image of the month,  nutritional studies,  Research

In addition to conducting groundbreaking biomedical research, Baylor College of Medicine is also creating better foods to address global food security issues.

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From The Labs

Not all cell types age equally – the Aging Fly Cell Atlas reveals how this happens

June 22, 2023 Aging fly,  aging mechanism,  cell atlas,  fruit fly,  Research,  single-nucleus RNA sequencing

The new atlas provides a powerful, open-access resource for scientists to better understand the biology of aging.

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From The Labs

Innovative machine-learning program reveals genes responsible for sex-specific differences in Alzheimer’s disease

June 20, 2023 Alzheimer's Disease,  Alzheimer's genes,  EAML,  Research,  sex differences,  small samples

This approach, called Evolutionary Action Machine Learning, enables researchers to probe smaller cohorts with greater accuracy.

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From The Labs

New biotech venture PHIOGEN, a spinoff of BCM’s TAILOR Labs, to tackle the global threat of antimicrobial resistance

June 15, 2023 antimicrobial resistance,  Bacteriophages,  BCM Ventures,  Biotechnology,  phage therapy,  Research,  TAILOR labs

PHIOGEN has developed a world-first technology platform that mobilizes the natural power of bacteriophages to tackle critical and life-threatening infections.

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A breast cancer cell dividing. Tubulin is shown in red, mitochondria in green and chromosomes in blue. National Cancer Institute/Wei Qian.
From The Labs

Delivering on the promise of personalized breast cancer therapy

June 13, 2023 anti-HER2 therapy,  HER2+ breast cancer,  multiparameter molecular classifier,  PIK3CA gene,  predicting response to therapy,  Research

A test predicts with a high degree of confidence which breast cancer patients would benefit the most from a therapy de-escalation approach.

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From The Labs

Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response

June 8, 2023 Breast Cancer,  cancer treatment,  Prostate Cancer,  Research,  SRC-3,  Tregs,  tumor microenvironment

The findings in animal models warrant continuing investigations to develop a novel, more effective and longer-lasting cancer therapy.

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From The Labs

Major primate genome sequencing studies reveal new insight into evolution, biodiversity and key applications for human health

June 6, 2023 biodiversity,  Evolution,  human health,  primate genome,  Research

These studies improve our understanding of both human biology and practical clinical issues.

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A person seen from behind who is holding their back as if in pain.
From The Labs

Gene Tiam1 orchestrates the development of chronic neuropathic pain

May 31, 2023 antisense oligonucleotides,  Chronic Pain,  gene Tiam1,  neuropathic pain,  Research,  spinal cord

The findings open new possibilities for novel therapies to provide much needed relief to patients with this condition.

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From The Labs

Changes in gene p16 create a permissive microenvironment for colon cancer growth

May 25, 2023 APC gene,  Colorectal Cancer,  DNA methylation,  epimutation,  p16,  polyps,  Research,  tumor microenvironment

The researchers also developed a strategy that reduced tumor growth and improved survival in tumor-bearing mice.

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From The Labs

Breast cancer tumors remotely disrupt immune response that could stop their own growth

May 23, 2023 anti-tumor response,  bone marrow microenvironment,  Breast Cancer,  MMP-13,  remote immunosuppression,  Research

The researchers identified ways to accelerate the restoration of the normal immune response and the efficacy of immunotherapies in animal models.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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