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The Cancer Genome Atlas

From The Labs

Tracking down microRNA candidates that can contribute to disease

November 6, 2018November 6, 2018 Ana Rodríguez 1 Comment ADmiRE, Cancer, developmental disease, gnomAD, heart disease, microRNA, The Cancer Genome Atlas, whole exome sequencing

What started as Ninad Oak’s side project turned out into something much larger, his doctorate thesis. “The project started as my qualifying exam that I

From The Labs

What activates the PI3K pathway, the most commonly mutated pathway in cancer that can be targeted by drugs?

July 31, 2017 Ana Rodríguez 0 Comments cancer mutations, Cancer pathways, IDH1 gene, personalized medicine, PI3K pathway, The Cancer Genome Atlas, VHL gene

The PI3K pathway has a number of diverse functions, including altering the cell’s metabolism and driving cell growth and proliferation. The PI3K pathway also is

From the Labs features an image pinpointing the location of Man1b1 inside the cell, which sharpened the view of cellular regulation of protein homeostasis. Image courtesy of the Sifers lab/Molecular Biology of the Cell, 2011.