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From The Labs

Unraveling how PTEN deficiency can lead to autism

November 19, 2019 antisense oligonucleotide,  Autism,  autism spectrum disorders,  mTOR,  PTEN,  Research

Autism is a developmental disorder that affects 1 in 59 children in the U.S. Mutations in specific genes, such as PTEN, can explain many autism

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From The Labs

A potential Achilles’ heel of breast cancer bone metastasis

December 6, 2018 Achilles' heel,  bone metastasis,  bone-in-culture,  Breast Cancer,  calcium,  mTOR,  Research

Researchers have found that the bone microenvironment can promote the growth and progression of breast cancer micrometastasis, a small group of cancer cells that separates

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From The Labs

Connecting mTOR and Src, two major players in cancer growth

November 27, 2018 cancer growth,  metabolism,  mTOR,  Research,  SRC

The protein complex known as mTORC1 is essential for the survival of all cells. It is at the heart of the mechanisms that regulate cellular

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From The Labs

Two is better than one, to improve brain function on a mouse model of Alzheimer’s disease

April 24, 2018 Alzheimer's Disease,  amyloid-beta,  mouse model,  mTOR,  Research

Many of the therapies that are currently being developed to treat Alzheimer’s disease focus on reducing the levels of amyloid-beta, a small protein that is

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From The Labs

The mTOR pathway: a new avenue for breast cancer cells to promote tumor growth

July 6, 2016 anti-tumor response,  Cancer,  cancer immunology,  G-CSF,  Immunology,  mTOR,  myeloid-derived suppressor cells (MDSCs)

Cancer cells respond in various ways to the body’s attempts to eliminate them. One strategy is to recruit immune cells in the body, such as

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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