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From The Labs

How the brain’s GPS helps you know where you are

March 26, 2024 brain GPS,  endocannabinoids,  epilepsy,  hippocampus,  memory problems,  place cells,  Research

Researchers show for the first time the role endocannabinoid signals play in living animals moving about in the environment.

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From The Labs

Restoring long-term memory recall in a mouse model of Rett syndrome

March 15, 2022 hippocampus,  long-term memory recall,  OLM cells,  Research,  Rett Syndrome,  SOM neurons

Researchers have discovered that diminished memory recall in Rett syndrome mice can be restored by activating specific inhibitory cells in the hippocampus.

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From The Labs

Hallucinogen drug LSD helps understand how the brain generates behavior

September 23, 2021 brain alterations,  brain map,  hippocampus,  LSD,  research behavior,  visual cortex

LSD triggers changes in the brain that may explain the profound altered behavior associated with the drug in animal models.

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From The Labs

This brain circuit allows the feeding and memory centers to talk to each other

February 19, 2019 appetite,  Brain,  chromosome 17,  hippocampus,  hypothalamus,  intellectual disability,  Memory,  NCOR1/2,  neurodevelopmental defects,  Research

It was not what the researchers were expecting to find when they set out to investigate how the protein complex NCOR1/2 regulates memory. “We knew

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From The Labs

How infrequent seizures may lead to persistent memory loss in Alzheimer’s disease

January 10, 2018 Alzheimer's Disease,  calbindin,  deltaFosB,  epilepsy,  epileptic seizures,  hippocampus,  memory loss

Even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models of Alzheimer’s disease; how this happens, however, has been difficult to explain.

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From The Labs

Lunatic Fringe gene and the renewable brain

October 30, 2017 hippocampus,  Lunatic Fringe,  neural sem cells,  neurons,  Notch signaling,  Renewable brain

The discovery that the brain can generate new cells – about 700 new neurons each day – has triggered investigations to uncover how this process

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From The Labs

‘Silent seizures’ discovered in patients with Alzheimer’s disease

July 10, 2017 Alzheimer's Disease,  deep brain,  eeg,  epilepsy,  epileptic seizures,  hippocampus,  nonconvulsive seizures,  seizures

Deep in the brains of two patients with Alzheimer’s disease, the main memory structure, the hippocampus, displays episodic seizure-like electrical activity. These nonconvulsive hippocampal seizures

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From The Labs

A new experimental system sheds light on how memory loss may occur

August 26, 2016 Alzheimer's Disease,  entorhinal cortex,  hippocampus,  ivermectin,  Memory,  Neuroscience

Two interconnected brain areas – the hippocampus and the entorhinal cortex – help us to know where we are and to remember it later.  It

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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