The process a developing embryo goes through to become a fully formed organism is complex and involves multiple steps. This sequence of events is orchestrated by the interactions of several families of proteins, many of which are not known.
Dr. Andy Groves, professor and Vivian L. Smith Endowed Chair in Neuroscience at Baylor College of Medicine, and Dr. Ankita Thawani, a postdoctoral associate in the Groves lab, investigate developmental processes and in a recent publication in the journal Development they report identifying Foxi3 as a necessary factor in mouse brain development.
The video of the month comes from this work. It shows the location of Foxi3 in the developing mouse embryo.
The video shows a whole embryo stained for Foxi3-GFP (green), SOX2 (red) and DAPI (blue). The top half of the egg shape is extraembryonic tissue, bottom half is embryonic. Video courtesy of the authors/Development, 2023.
Read more about the research in the Groves lab, here.
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