Profile feature: Dr. Adam Kuspa
The following insideview interview appeared in Nature Outlook Supplement on Research Commercialization, May 5, 2016. Baylor College of Medicine (BCM) has built a reputation as a
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From The Labs
Crystal structure of PKGI suggests a new activation mechanism
By Ana María Rodríguez, Ph.D. Kinases form a large family of proteins that seem to be involved in nearly every aspect of cell life. Faulty
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Born to run? Study suggests love of exercise starts in the womb
By Ana María Rodríguez, Ph.D. When pregnant female mice exercise their offspring receive an unexpected benefit; they tend to be more physically active than mice
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Genomic study on renal cell carcinoma reveals potential opportunities for more effective treatments
By Ana María Rodríguez, Ph.D. It is well understood that renal cell carcinoma is not a single disease. Patients with this type of cancer have
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Evolution meets biochemistry to better understand how dopamine receptors work
When proteins fail at doing their job, disease usually follows. To perform their job, proteins need to maintain a particular structure and specific motions,
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Understanding obesity from the inside out: new lab method reveals roles of GABA in the control of appetite and metabolism
By Ana María Rodríguez, Ph.D. The average American is more than 24 pounds heavier today than in 1960. Around the world, obesity has more than
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Discovery of CTLA-4 in dendritic cells opens new possibilities to fight cancer
By Ana María Rodríguez, Ph.D. In the battle against cancer, T cells are the ‘foot soldiers’ and dendritic cells are ‘the generals.’ Cancer cells are
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One atom can make a difference: Hydrogen-bonding pairing helps design better drugs to neutralize gut bacterial infections
IP6, the natural inhibitor or ligand of Clostridium difficile’s toxin, binds weakly to the toxin. This results in the toxin remaining active (center figure). Changing
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Social amoeba cast wide, lethal DNA nets to kill invading bacteria
By Ruth SoRelle, M.P.H. The amoeba Dictyostelium discoideum begins as a soil-dwelling single cell organism. When stressed, many individual cells coalesce to form first a slug
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Image of the Month – Triple immunofluorescence of MCF-7 breast cancer cells.
IMAGE OF THE MONTH: MCF-7 breast cancer cells: Triple immunofluorescence for estrogen receptor (in red), androgen receptor (in green) and glucocorticoid receptor (in blue) demonstrates marked
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