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Monday, December 15, 2025

Latest:

Jingle all the way to an allergy-free holiday
From symptoms to solutions: How new guidelines are changing UTI care in spinal cord injury patients
Research suggests that Alzheimer’s disease may develop through distinct biological pathways
Sweat vs. sweets: The workout math behind holiday treats
Researchers make strides toward preventing parenteral nutrition-associated liver disease

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Search Results for: O'Malley

In Memoriam: Bert W. O’Malley, M.D.

November 13, 2025 androgen receptor, Cancer, circadiam rhythm, endocrinology, estrogen, memoriam, Research, SRC-2, SRC-3

During his decades-long career, Dr. Bert O’Malley changed our understanding of endocrinology in a fundamental way.

Baylor researchers awarded the National Academy of Sciences 2023 Cozzarelli Prize in Biomedical Sciences

March 19, 2024 Awards, Breast Cancer, Cozzarelli Prize, National Academy of Sciences, PNAS, Prostate Cancer, Research, SRC-3

The research warrants continuing investigations to translate the findings into a novel, more effective and longer-lasting cancer therapy.

Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response

June 8, 2023 Breast Cancer, cancer treatment, Prostate Cancer, Research, SRC-3, Tregs, tumor microenvironment

The findings in animal models warrant continuing investigations to develop a novel, more effective and longer-lasting cancer therapy.

A collage of microscopic images of different human cells.

Entanglement within a (transcriptional) bubble explains finely tuned regulation of gene expression

February 7, 2023 enhancer-promoter interactions, entanglement, gene expression, Research, transcriptional bubble

Researchers discovered that transcription of enhancers and promoters is interdependent and propose a mechanism to explain it.

Throwback Thursday: The first Image of the Month

August 11, 2022 DNA-dependent protein kinase, estrogen receptor alpha, Image of the month, Research, science cartoon, Throwback Thursday

For years after the first one was posted, we have continued to feature amazing research images from Baylor labs every month.

SRC-3 is a key regulator of the 12-hour clock

March 10, 2022 12-hour biological clock, chronotherapeutics, circadian rhythm, circatidal rhythm, Research, SRC-3, tides, XBP1

Altered 12-hour cycles have been associated with human diseases and hundreds of genes have been identified that are activated in 12-hour cycles.

Image of the month: This brain region coordinates survival adaptations to food shortages

January 4, 2022 behavioral adaptations, fasting, food shortage, hippocampal dentate gyrus, metabolic adaptations, Research, SCR-2

SRC-2 (green) in POMC neurons in the hypothalamus helps animals survive when food is hard to find.

The multitasking nature of SRC-3

March 23, 2021 Breast Cancer, cancer survival, immune system, Research, SRC-3, steroid hormone, T regulatory cells

SRC-3 not only influences steroid hormone function and gives a heads up for aggressive human breast cancer, it also regulates immune T cells.

MCB-613 helps the heart heal itself after a heart attack

December 17, 2020 heart attack, heart failure, heart repair and regeneration, MCB-613, Research, SRC-3

MCB-613 after a heart attack prevented the scar and maladaptive repair of heart tissue that can lead to heart failure.

The N-terminal domain of the androgen receptor is at the heart of its action

July 30, 2020 androgen receptor, C-terminal domain, coactivators, n-terminal domain, Prostate Cancer, Research, testosterone

Detailed 3-D studies reveal how the androgen receptor is put together as a functional complex that drives prostate cancer.

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